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What began as an apparent simple disagreement between the camps of Manny Pacquiao and Floyd Mayweather Jr. over how to handle drug testing for their megafight — tentatively scheduled for March 13 at the MGM Grand in Las Vegas — has spiraled so out of control that the potential biggest money fight in boxing history was in serious jeopardy on Christmas Day.

Pacquiao, angered by accusations from the Mayweather camp that he uses performance-enhancing drugs, said he would file a defamation lawsuit against Mayweather and Golden Boy Promotions.

“Enough is enough. These people, Mayweather Sr., [Mayweather] Jr. and Golden Boy Promotions, think it is a joke and a right to accuse someone wrongly of using steroids or other performance-enhancing drugs,” said Pacquiao, who denied that he has ever used any banned substance and who has passed all of his drug tests. “I have tried to just brush it off as a mere prefight ploy, but I think they have gone overboard.”

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